School of Computing

A virtual lab for exploring the [PSI]+ yeast prion

Jacqueline L. Whalley, Mick F. Tuite, and Colin G. Johnson

In Faramarz Valafar, editor, Proceedings of the International Conference on Mathematics and Engineering Techniques in Medicine and Biological Sciences, volume II, pages 182-196. CSERA Press, June 2002.

Abstract

This paper discusses on going work on simulating the propogation within the cell of a prion protein in yeast. The biological background to the project is outlined, and a number of questions about this system are posed. The paper then discusses how computer simulation is being used to provide a "virtual laboratory" for this system, which will be employed to support and understand real experiments. Futhermore, the development of the application is detailed with emphasis on the challenges encountered to date.

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Bibtex Record

@inproceedings{1398,
author = {Jacqueline L. Whalley and Mick F. Tuite and Colin G. Johnson},
title = {A virtual lab for exploring the [{P}{S}{I}]+ yeast prion},
month = {June},
year = {2002},
pages = {182-196},
keywords = {determinacy analysis, Craig interpolants},
note = {},
doi = {},
url = {http://www.cs.kent.ac.uk/pubs/2002/1398},
    publication_type = {inproceedings},
    submission_id = {19599_1027329475},
    ISBN = {1-892512-32-7},
    booktitle = {Proceedings of the International Conference on Mathematics and Engineering Techniques in Medicine and Biological Sciences},
    editor = {Faramarz Valafar},
    volume = {II},
    publisher = {CSERA Press},
    refereed = {Yes},
}

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